Drug interaction between tacrolimus and nilotinib in a patient with chronic myeloid leukemia after renal transplant

نویسندگان

  • Takashi Onaka
  • Naoto Takahashi
  • Masatomo Miura
  • Akihito Yonezawa
چکیده

Nilotinib, a BCR-ABL tyrosine kinase inhibitor, is a known inhibitor of CYP3A4 and could increase the concentration of drugs metabolized by CYP3A4. An immunosuppressive drug for nilotinib-treated patients following transplant should be administered with careful pharmacokinetic monitoring because of its interaction with nilotinib.

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عنوان ژورنال:

دوره 5  شماره 

صفحات  -

تاریخ انتشار 2017